On Acute Tubercle

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On the nucleoproteins of avian tubercle bacilli.

The nucleic acids of tubercle bacilli have formed the subject of several studies, among which may be mentioned those by Ruppel (l), Levene (2), and Johnson and his associates (3-5). The work of Mensel and Heidelberger (6) on the fractionation of the proteins of the tubercle bacillus revealed the presence of several protein fractions, rich in phosphorus and in purines, which appeared to be nucle...

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The Effect of Spermine on Tubercle Bacilli

A crystalline substance capable of suppressing the growth of a variety of mycobacteria in vitro has been isolated from extracts of tissue in acidified dilute ethanol. This inhibitory material was found to be equally active against virulent, attenuated, and avirulent variants of human and bovine tubercle bacilli, but had little or no effect on saprophytic mycobacteria and on several non-acid-fas...

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Studies on the Virulence of Tubercle Bacilli

The bacillary cords characteristic for virulent tubercle bacilli are readily disrupted when wet bacilli are suspended in hydrocarbons such as paraffin oil or petroleum ether. The disruption of cords is due to the removal of a material coating the surface of the bacilli and causing them to adhere to each other. This material can be obtained from virulent bacilli by extracting them with petroleum...

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Studies on Tubercle Bacillus-histiocyte Relationship

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ژورنال

عنوان ژورنال: BMJ

سال: 1868

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.383.426